Function of B-Cells and Insulin Resistance in Long-Standing Type 2 Diabetes Mellitus

Abstract

Introduction. Every patient with type 2 diabetes mellitus secretes less insulin than
necessary for his/her level of insulin sensitivity, and many of them have some degree
of insulin resistance. The mix of insulin defi ciency and insulin resistance is different
for each patient and, in any patient, it may vary during the course of the disease. The
aim of our study was to examine the degree of