Acute Poisoning with Herbicide Glyphosate


  • Milidrag Vukotić
  • Vesna Paleksić
  • Slaviša Narić



Glyphosate is the most common used organophosphorus herbicide which most probably inhibits oxidative phosphorylation without leading to the inhibition of esterases. Glyphosate poisoning is mostly the consequence of the synergistic effect of an active substance and surfactant. There is a case of 42-year-old patient who worked on weed spraying with glyphosate, with hand sprinkler. Symptoms of the acute poisoning such as weakness, sweating, nausea, vomiting and stomach ache were visible right after the working period. With biochemical analysis increased activity of the enzymes AST, ALT and y-GT were diagnosed and sanated after aborting an expositions in the period of six months and treatment. In this shown case poisoning was caused during applying herbicides without proper handling with the herbicide and also because of non-compliance of measures in safety and health at work. It is very clear that this is a case of acute poisoning with pesticides which ended with no consequences and was declared as work injury.