Hemolysis - a constant source of error in laboratory diagnostics // Hemoliza – stalni izvor greške u laboratorijskoj dijagnostici


  • Nevena Kutlija ZU Alfalab, Banja Luka




The aim of this paper is to point out the importance of proper pre-analytical preparation of the sample in order to reduce the number of errors in the laboratory with a special emphasis on hemolysis. In recent years, the lab has become more efficient in terms of faster results, more precise, faster and more precise controls, all due to automation, but it needs to be cautious as errors continue to occur. The largest share of errors occurs in the pre-analytic and post-analytical phase. The erythrocyte hemolysis in vivo or in vitro is one of the most significant errors in the preanalytic phase
This is a literature review. The period of review of the literature is from 20-31 May 2017. The literature review was carried out in the HINARI, PUB MED and GOOGLE SEARCH databases. A total of 120 scientific articles were examined, mostly in English, of which 20 were put into operation. By reviewing the summary of each article, all articles that did not write about hemolysis, as a source of error are excluded.
A review of literature through research carried out in the world and in our country, it turned out that the error in laboratory diagnostics still persists. The greatest number of errors occurs in the pre-analytical phase of work. According to the latest research, hemolysis takes the first place from mistakes in the pre-analytic phase of the laboratory process.
Conclusion: Laboratory analytical work results must meet the requirements of analytical accuracy and precision and the clinical benefit of the analysis. The basic requirement for achieving the greatest possible quantitative reduction of laboratory errors is team work and inter-clinical cooperation. Laboratory experts must take the lead in ensuring patient safety both inside and outside the walls of clinical laboratories.