DIFFERENT TYPES OF COLORECTAL CARCINOMA CHARACTERIZATION USING STAINED AND NON STAINED PLATES BY OPTO-MAGNETIC SPECTROSCOPY
DOI:
https://doi.org/10.7251/COMEN1401161DAbstract
According to the World Health Organization cancer is the leading cause of death worldwide and on the third place is the most common and dangerous colorectal cancer with the rate of 17.3/100,000 people. Therefore, it is necessary to find effective solutions to improve the quality and speed of diagnostic tools so that they can respond to the challenges of prevention strategies which are an integral part of the rapid diagnosis of a large number of patients. The objectives of the research conducted in this study (in vitro) are: (1) examining the possibilities of application of opto-magnetic imaging spectroscopy for characterization between different types of colon cancer, stained and non-stained plates, (2) method validation, (3) parameters determination for research in in vivo conditions, and (4) application in clinical trial to increase the efficiency and give more reliable diagnosis. In this paper we present Opto-magnetic imaging spectroscopy (OMIS) as a novel optical method for differentiation of different types of colon cancer, significant similarity between stained and non-stained plates based on light-tissue interaction. Results have showed that OMIS can make a difference between colorectal carcinoma and other types of colon cancer, as well as prove that plates staining can be avoided.References
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[3] J. Ferlay, P. Autier, M. Boniol, M. Heanue, M. Colombet, P. Boyle, Estimates of the cancer incidence and mortality in Europe in 2006, Ann Oncol, Vol. 18 (2007) 581−592.
[4] M. Papić-Obradović, Rana dijagnostika epitelnih tkiva [Early diagnostics of epithelial tissue cancer], Beograd, 2012. (in Serbian).
[5] M. Papić-Obradović, D. Kojić, A. Tomić, L. Matija, Dj. Koruga, Novel method of Epstain-Barr virus detection in blood plasma of pregnant women by digital images of opto-magnetc finger-print, Conference Proceedings Contemporary Materials, Academy of Sciences and Arts of the Republic of Srpska, Banja Luka 2010, 127−136.
[6] Đ. Koruga, S. Miljković, S. Ribar, L. Matija, D. Kojić, Water Hydrogen Bonds Study by Op-to-Magnetic Fingerprint, Acta Physica Polonica A, Vol. 117−5 (2010) 777−781.
[7] M. Papić-Obradović, D. Kojić, L. Matija, Opto-Magnetic Method for Epstein – Barr Virus and Cytomegalovirus Detection in Blood Plasma Samples, Acta Physica Polonica A, Vol. 117−5 (2010) 782−784.
[8] Dj. Koruga, J. Bandić, G. Janjić, C. Lalović, J. Munćan, D. Dobrosavljević Vukojević, Epidermal layers characterisation by opto-magnetic spectroscopy based on digital image of skin, Acta Physica Polonica A, Vol. 121−3 (2012) 1111−1115.
[9] D. Stamenković, D. Kojić, L. Matija, Z. Miljković, B. Babić, Physical Properties of Contact Lenses Characterized by Scanning Probe Microscopy and Opto-Magnetic Fingerprint, International Journal of Modern Physics B, Vol. 24 (6−7) (2010) 825−834.
[10] Đ. Koruga, A. Tomić, System and Method for Analysis of Light-matter Interaction Based on Spectral Convolution, US Patent Pub. No.: 2009/0245603, Pub. Date: Oct. 1, 2009
[11] D. Kojić, Karakterizacija strukturalnih, mehaničkih, električnih i magnetnih osobina kože pomoću optičkog i nanoprobe mikroskopa [Characterisation of structural, mechanical, electrical and magnetic properties of skin by optical and nanoprobe microscopy], Doctoral dissertation, mentor prof. Djuro Koruga, Faculty of Mechanical Engineering, University of Belgrade, 2010 (in Serbian).
[12] B. Jeftić, M. Papić Obradović, G. Nikolić, A. Dragičević, J. Šakota Rosić, M. Tomić, L. Matija, Study of stained and unstained PAP smears using optomagnetic imaging spectroscopy, Sixth international scientific conference Contemporary Materials 2013, Book of Abstracts, Banja Luka 2013, 110.
[13] Q. B. Li, Z. Xu, N. W. Zhang, L. Zhang, F. Wang, L. M. Yang, J. S. Wang, S. Zhou, Y. F. Zhang, X. S. Zhou, J. S. Shi, J. G. Wu, In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy, World J Gastroenterol, Vol. 11−3 (2005) 327−30.
[14] H. Wei, et al., Differences in optical properties between healthy and pathological human colon tissues using a Ti:sapphire laser: an in vitro study using the Monte Carlo inversion technique, J. Biomed. Opt., Vol. 10−4 (2005), 1083−3668
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2014-09-26
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