DEVELOPMENT OF LONG-LASTING ANTIMICROBIAL AND POTENTIAL HEMOSTATIC NANOCOMPOSITES (pyrophyllite based) WITH PVP-coated COLLOIDAL SILVER NANOPARTICLES

Authors

  • Janja Todorović University of Banja Luka, Faculty of Natural Sciences and Mathematics, Chemistry Department, dr. Mladena Stojanovića 2, 78 000 Banja Luka, Bosnia and Herzegovina
  • Mirzeta Saletović University of Tuzla, Faculty of Natural Sciences and Mathematics, Chemistry Department, Irfeta Vejzagića 4, 75 000 Tuzla, Bosnia and Herzegovina
  • Dijana Mihajlović University of Banja Luka, Faculty of Agriculture, Bulevar vojvode Bojovića 2a, 78 000 Banja Luka, Bosnia and Herzegovina
  • Dragana Gajić University of Banja Luka, Faculty of Natural Sciences and Mathematics, Chemistry Department, dr. Mladena Stojanovića 2, 78 000 Banja Luka, Bosnia and Herzegovina
  • Dragana Blagojević University of Banja Luka, Faculty of Natural Sciences and Mathematics, Chemistry Department, dr. Mladena Stojanovića 2, 78 000 Banja Luka, Bosnia and Herzegovina
  • Dijana Jelić University of Banja Luka, Faculty of Natural Sciences and Mathematics, Chemistry Department, dr. Mladena Stojanovića 2, 78 000 Banja Luka, Bosnia and Herzegovina

DOI:

https://doi.org/10.7251/COMEN2201092T

Abstract

Pyrophyllite clay, modified with PVP coated silver nanoparticles (PYRO-PVP/AgNPs), with recently proved antibacterial activity was prepared. Silver nanoparticles were synthesized by the chemical reduction method of AgNO3 using NaBH4 and poly(vinyl pyrrolidone) (PVP) as a stabilizer and excellent dispersant. This research aimed to elucidate the mechanisms and kinetics of AgNPs, along with the PVP protective mechanism responsible for antibacterial activity towards the microorganisms. Pioneering steps were made toward coagulation studies due to the potential of aluminosilicate layered clays to serve as alternatives to hemostatic agents currently in use. The isoelectric point of pyrophyllite samples with 5, 20, and 45 μm diameter particles and PYRO/PVP/AgNPs sample (Ag25mg/L) was evaluated to understand how the anticoagulant or procoagulant properties of the pyrophyllite varied according to the pH of the isoelectric point. Characterization of the PYRO-PVP/AgNPs samples was performed using FTIR spectroscopy, while the release mechanism and kinetics of silver ions were monitored using atomic absorption spectroscopy (AAS). Additionally, AAS was used for the evaluation of heavy metals content in pyrophyllite clay and a simple, cost-effective procedure was proposed for the extraction of heavy metals.

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Published

2022-07-06

Issue

Vol. 13 No. 1 (2022): Contemporary Materials XIII‒1

Section

Articles