USE OF 3D-BIOPRINTING IN TISSUE ENGINEERING SCAFFOLD PRODUCTION

Authors

  • Nebojša Zdravković University of Kragujevac, Faculty of Medical Sciences, Kragujevac, Serbia
  • Marko N. Zivanović University of Kragujevac, Institute of Information Technologies, Kragujevac, Serbia
  • Nikolina Kastratović University of Kragujevac, Faculty of Medical Sciences, Kragujevac, Serbia
  • Jelena Grujić University of Kragujevac, Institute of Information Technologies, Kragujevac, Serbia
  • Katarina Virijević University of Kragujevac, Institute of Information Technologies, Kragujevac, Serbia
  • Dalibor Nikolić University of Kragujevac, Institute of Information Technologies, Kragujevac, Serbia
  • Nenad Filipović University of Kragujevac, Faculty of Engineering, Kragujevac, Serbia

DOI:

https://doi.org/10.7251/COMEN2301019Z

Abstract

3D bioprinting is the hi-tech approach in tissue engineering science. Applying of modern 3D bioprinting systems allows production of tissue-like structures that could be used in regenerative medicine. Such tissues or primitive organ constructs could be used for substituting the parts of damaged organs, or for changing of organs in whole. Biomaterials must fulfill specific requirement to be applied in regenerative medicine: biocompatibility, biodegradability and possessing appropriate mechanical properties. PEG and PCL are widely used today in tissue engineering. We optimized wide range of PCL, PEG solutions alone and in combination. For 3D bioprinting was used Inkredible+ device. Optimization of experimental parameters for creating a scaffold that can be used in tissue engineering is a demanding process. As it is the first stage of developing the blood vessel, there is a high importance of ensuring they are formed well and with the desired properties. This innovative approach may be promising for further fabrication of a blood vessel.

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Published

2023-06-27

Issue

Vol. 14 No. 1 (2023): Contemporary Materials XIV‒1

Section

Articles